SARS-CoV-2 Spike RBD L452R, E484Q (India Variant) Recombinant Protein

SARS-CoV-2 Spike RBD L452R, E484Q (India Variant) Recombinant Protein
Artikelnummer
AVIOPSN00009-100
Verpackungseinheit
100µg
Hersteller
Aviva Systems Biology

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Conjugation: Unconjugated.

Description: The SARS-CoV-2 Spike Receptor Binding Domain L452R, E484Q (India Variant) Recombinant Protein (OPSN00009) is expressed in Sf9 Baculovirus cells and includes a C-terminal Avidin-His Tag with purification via IMAC. The sequence includes amino acids 319-357 of the lineage B.1.617.1, L452R/E484Q SARS-CoV-2 spike sequence first identified in India. Suitable for Biotinylation and Protein:Protein Interaction assays in a variety of formats.

Description of Target: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ The structural proteins of SARS-CoV-2 include the envelope protein (E), spike or surface glycoprotein (S), membrane protein (M) and the nucleocapsid protein (N). The spike glycoprotein is found on the outside of the virus particle and gives coronavirus viruses their crown-like appearance. This glycoprotein mediates attachment of the virus particle and entry into the host cell. S protein is an important target for vaccine development, antibody therapies and diagnostic antigen-based tests.

Key Reference: Cuff, Madeleine (19 April 2021). "Indian variant: Cases of new 'double mutation' Covid strain thought to be spreading in UK". i. London. Retrieved 20 April 2021.

Molecular Weight: 30kDa.

Product Format: Liquid. 50 mM Tris-HCL, 1M NaCl, pH 7.5.

Protein Name: surface glycoprotein.

Protein Size: AA 319-537, L452R/E484Q (India Variant).

Purification: IMAC.

Purity: 0,9.

Tag: C-Avitag/His
Mehr Informationen
Artikelnummer AVIOPSN00009-100
Hersteller Aviva Systems Biology
Hersteller Artikelnummer OPSN00009-100
Verpackungseinheit 100µg
Mengeneinheit STK
Reaktivität SARS-Coronavirus
Methode Functional Assay, In Vitro
Human Gene ID 43740568
Wirt Baculovirus
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