Allitinib tosylate, CAS 1050500-29-2

Product Description: Allitinib tosylate (AST-1306 (TsOH)) is an orally active and irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. Allitinib tosylate also inhibits ErbB4 with an IC50 of 0.8 nM. Allitinib tosylate is an anilino-quinazoline compound and has anti-cancer activity[1]

Applications: Cancer-Kinase/protease

Formula: C31H26ClFN4O5S

References: [1]Xie H, Lin L, Tong L et al. AST1306, a novel irreversible inhibitor of the epidermal growth factor receptor 1 and 2, exhibits antitumor activity both in vitro and in vivo. PLoS One. 2011;6(7):e21487.

CAS Number: 1050500-29-2

Molecular Weight: 621.08

Compound Purity: 99.83

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: EGFR

• Artikelnummer: MEXHY-13427-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-13427-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK