CloneID: TAN 1-7
Heavy Chain modification: Fc Silent™
Antigen Long Description: Recombinant mouse CD70 (extracellular domain, aa residues 41-195).
Buffer Composition: PBS only.
Chimeric Use Statement: This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: Q05A52
Specificity Statement: This antibody binds to mouse CD70.
Application Notes (Clone): This antibody can be used to detect mouse CD70, the ligand for CD27. The original rat IgG1 format has been used in vivo to inhibit CD70-CD27 mediated induction of interferon gamma following injection of glycolipid activators .