Anti-E-protein DIII (LR) (ZV-67)

Anti-E-protein DIII (LR) (ZV-67), Recombinant, IgG2c kappa, Host: Mouse

CloneID: ZV-67

Antigen Long Description: This antibody was generated by infecting mice with 1000 FFU of ZIKV MR-766 followed by a booster at 30d post-infection of ZIKV H/PF/2013, respectively and given a final intravenous boost with live ZIKV DIII (amino acids 299 to 407 of the ZIKV E protein))

Buffer Composition: PBS only.

Specificity Statement: ZV-67 binds to the Zika virus envelope protein at domain III (DIII, LR). No cross-reactivity with other tested flaviviruses has been reported.

Application Notes (Clone): The original mouse IgG2c format has been shown to have neutralizing activity and has been used to label ZIKV infected cells (4% PFA fixation, 0.1% saponin permeabilization). Yi et al. (PMID: 29033368) used this antibody for Western Blotting at a concetnration of 0.5 ug/ml.

• Artikelnummer: ABAAb00812-4.0-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab00812-4.0-BT
• Verpackungseinheit: 500 μg
• Mengeneinheit: STK
• Reaktivität: Virus
• Klonalität: Recombinant
• Methode: Western Blotting, Flow Cytometry, Neutralization, Surface Plasmon Resonance (SPR)
• Isotyp: IgG2c kappa
• Wirt: Mouse