CloneID: F9
Heavy Chain modification: ScFv
Antigen Long Description: The original antibody was isolated from a human scFv phage display library by panning against biotinylated fluoroquinolone antibiotic.
Origin Pub PMID: 21142055
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted human scFv antibody, based on the original human scFv format, created for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody is a general fluoroquinolone binder that likely binds to the antigen at the common pyridone-carboxylic acid pharmacophore.
Application Notes (Clone): This antibody was capable of binding the biotin analogue of fluoroquinolone in an ELISA. The binding affinity of the original scFv antibody to norfloxacin-biotin analogue was reported to be Kd = 1.58 µM. This antibody was used in the development of an ScFv biosensor for qualitative detection of antibiotics in livestock drinking water (PMID: 21142055),
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