CloneID: 17-3-4-1
Heavy Chain modification: Fc Silent™
Antigen Long Description: This antibody was raised by immunising BALB/c mice with hapten N6-methyladenosine-5’-monophosphate conjugated to BSA
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Specificity Statement: This antibody is specific for N(6)-methyladenosine, a modified base found frequently in the mRNA of all higher eukaryotes and Saccharomyces cerevisiae. It recognises N(6)-methyladenosine 6A in single-stranded nucleic acids, including both DNA and RNA.
Application Notes (Clone): This antibody has been used in immunoprecipitation experiments to identify the presence of N(6)-methyladenosine within mRNA transcripts bound to oligo(dT) magnetic beads (Bodi et al, 2010). It has been characterised using immunoblot analysis (Bodi et al, 2010).
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