Clone Name: HL3798
Light Chain: Kappa
Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Specificity/Sensitivity: This antibody detects Cardiac Troponin I protein when dually phosphorylated at Ser23 and Ser24, but it does not recognize Cardiac Troponin I protein when singly phosphorylated at Ser23 or Ser24.
Form: Liquid
Buffer (with preservative): PBS, no preservatives.
Concentration: batch dependent (Please refer to the vial label for the specific concentration.)
Background: Predicted to enable several functions, including calcium channel inhibitor activity; calcium-dependent protein binding activity; and cytoskeletal protein binding activity. Acts upstream of or within several processes, including circulatory system development; intracellular calcium ion homeostasis; and regulation of systemic arterial blood pressure by ischemic conditions. Located in sarcomere. Part of cardiac Troponin complex. Is expressed in several structures, including alimentary system; central nervous system; heart; integumental system; and sensory organ. Used to study hypertrophic cardiomyopathy 7 and restrictive cardiomyopathy. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple). Orthologous to human TNNI3 (troponin I3, cardiac type). [provided by Alliance of Genome Resources, Jul 2025]
Uniprot ID: P48787
Antigen Species: Mouse
Immunogen: Carrier-protein conjugated synthetic peptide surrounding phospho Ser23/Ser24 of mouse Cardiac Troponin I. The exact sequence is proprietary.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: troponin I, cardiac 3
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