ME3221, CAS 139958-16-0

Product Description: ME3221 is an angiotensin AT1 receptor antagonist that effectively antagonizes the pressor response to angiotensin II in rats and marmosets without affecting the hypotensive response to bradykinin. It demonstrates potent antihypertensive effects in renal hypertensive rats and spontaneously hypertensive rats (SHR), with efficacy comparable to or better than losartan in vivo. ME3221's repeated administration in SHR results in sustained and stable hypotensive effects without affecting heart rate, indicating its potential for treating both renal and essential hypertension similarly to losartan[1].

Applications: Neuroscience-Neuromodulation

Formula: C22H21N5O2

References: [1]Pharmacological profile of ME3221, a novel angiotensin II receptor antagonist

CAS Number: 139958-16-0

Molecular Weight: 387.43

Research Area: Cardiovascular Disease

Target: Angiotensin-converting Enzyme (ACE)

• Artikelnummer: MEXHY-121550-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-121550-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK