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VPS35 Kit
Colorimetric measurement of VPS35
Artikelnummer
STRSKT-141-96
Verpackungseinheit
96 well
Hersteller
Stressmarq Biosciences
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Target: VPS35.
Product Type: ELISA Kits.
Trademark: MOLECULAR SIGNATURE®.
Detection Method: Colorimetric Assay.
Assay Type: Competitive ELISA (Enzyme-linked Immunosorbent Assay).
Utility: ELISA kit used to quantitate VPS35 in samples.
Sample Type(s): Tissue, Cell Lysate.
Number of Samples: 40 samples in duplicate.
Incubation Time: 3 hours.
Sensitivity: 50 pg/mL.
Assay Range: 78.125 - 5000 pg/mL.
Scientific Background: Vacuolar Protein Sorter-35 (VPS35) is a component of the retromer complex, which is essential for endosome-to-Golgi retrieval of membrane proteins. VPS35 mutations such as D620N have been linked to Parkinson’s Disease (PD) (1,2) and affect retromer function, protein homeostasis, and mitochondria (3).
References: 1. Vilarino-Guell, C. et al. (2011) Am J Hum Genet 89:162–1672. Zimprich, A. et al. (2011) Am J Hum Genet 89:168–1753. Rahman, A.A., Morrison, B.E. (2019) Neurosci 401:1-10.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Product Type: ELISA Kits.
Trademark: MOLECULAR SIGNATURE®.
Detection Method: Colorimetric Assay.
Assay Type: Competitive ELISA (Enzyme-linked Immunosorbent Assay).
Utility: ELISA kit used to quantitate VPS35 in samples.
Sample Type(s): Tissue, Cell Lysate.
Number of Samples: 40 samples in duplicate.
Incubation Time: 3 hours.
Sensitivity: 50 pg/mL.
Assay Range: 78.125 - 5000 pg/mL.
Scientific Background: Vacuolar Protein Sorter-35 (VPS35) is a component of the retromer complex, which is essential for endosome-to-Golgi retrieval of membrane proteins. VPS35 mutations such as D620N have been linked to Parkinson’s Disease (PD) (1,2) and affect retromer function, protein homeostasis, and mitochondria (3).
References: 1. Vilarino-Guell, C. et al. (2011) Am J Hum Genet 89:162–1672. Zimprich, A. et al. (2011) Am J Hum Genet 89:168–1753. Rahman, A.A., Morrison, B.E. (2019) Neurosci 401:1-10.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
| Artikelnummer | STRSKT-141-96 |
|---|---|
| Hersteller | Stressmarq Biosciences |
| Hersteller Artikelnummer | SKT-141-96 |
| Verpackungseinheit | 96 well |
| Mengeneinheit | PAK |
| Reaktivität | Human, Mouse (Murine), Rat (Rattus) |
| Methode | ELISA (competitive) |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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