Clone Name: GT111
Application Note: WB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Specificity/Sensitivity: This antibody is specific for human GZMB protein and does not cross react with human GZMH protein.
Form: Liquid
Buffer (with preservative): PBS, no preservatives.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]
Uniprot ID: P10144
Antigen Species: Human
Immunogen: Synthetic peptide of human Granzyme B.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: granzyme B
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