Product Description: Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins[1][2].
Applications: Metabolism-protein/nucleotide metabolism
Formula: CH6ClN3
References: [1]Y Hagihara, et al. Guanidine hydrochloride-induced folding of proteins. J Mol Biol. 1993 May 20;231(2):180-4./[2]G Jung, et al. Guanidine hydrochloride inhibits Hsp104 activity in vivo: a possible explanation for its effect in curing yeast prions. Curr Microbiol. 2001 Jul;43(1):7-10./[3]Saeed Emadi, et al. A comparative study on the aggregating effects of guanidine thiocyanate, guanidine hydrochloride and urea on lysozyme aggregation. Biochem Biophys Res Commun. 2014 Aug 8;450(4):1339-44./[4]E C Herrmann Jr, et al. Prevention of death in mice infected with coxsackievirus A16 using guanidine HCl mixed with substituted benzimidazoles. Antiviral Res. 1982 Dec;2(6):339-46.
CAS Number: 50-01-1
Molecular Weight: 95.53
Compound Purity: 99.9
Research Area: Metabolic Disease; Cancer
Solubility: DMSO : ≥ 100 mg/mL/H2O : 100 mg/mL (ultrasonic)
Target: Autophagy;Endogenous Metabolite
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