Product Description: Natamycin (Pimaricin) is a macrolide antibiotic agent produced by several Streptomyces strains. Natamycin inhibits the growth of fungi via inhibition of amino acid and glucose transport across the plasma membrane. Natamycin is a food preservative, an antifungal agent in agriculture, and is widely used for fungal keratitis research[1][2].
Applications: COVID-19-immunoregulation
Formula: C33H47NO13
References: [1]Wu H, et al. SlnM gene overexpression with different promoters on natamycin production in Streptomyces lydicus A02. J Ind Microbiol Biotechnol. 2014 Jan;41(1):163-72./[2]Yvonne Maria te Welscher, et al. Polyene antibiotic that inhibits membrane transport proteins. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11156-9.
CAS Number: 7681-93-8
Molecular Weight: 665.73
Compound Purity: 99.07
Research Area: Infection
Solubility: DMSO : 15.38 mg/mL (ultrasonic;adjust pH to 3 with 1 M HCl)/H2O : < 0.1 mg/mL
Target: Antibiotic;Bacterial;Endogenous Metabolite;Fungal