Phenylbutazone-d9, CAS 1189479-75-1

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 4-(butyl-d9)-1,2-diphenyl-3,5-pyrazolidinedione

Purity: ≥99% deuterated forms (d1-d9)

Formula Markup: C19H11D9N2O2

Formula Weight: 317.42892

CAS Number: 1189479-75-1

Notes: Phenylbutazone-d9 is intended for use as an internal standard for the quantification of phenylbutazone (Item No. 70400) by GC- or LC-MS. Phenylbutazone is a non-steroidal anti-inflammatory drug and an inhibitor of the peroxidase activity of COX (IC50 = ~100 µM in the presence of hydrogen peroxide).{807} It also inhibits prostaglandin I synthase (IC50 = ~25 µM in the presence of hydrogen peroxide). Phenylbutazone (2 mg/kg) reduces increases in type II collagen levels in the inflamed joints of an equine model of LPS-induced acute synovitis.{60463} Formulations containing phenylbutazone have been used in the treatment of lameness in horses.

• Artikelnummer: CAY33978-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33978-500
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung