Anti-CD8 (14)

Anti-CD8 (14), Recombinant, IgG1 kappa, Host: Mouse

CloneID: 14

Antigen Long Description: Murine antibodies were produced by immunising mice with human monocytes. Immunised cells were used to produce a hybridoma from which the antibodies were purified.

Buffer Composition: PBS only.

Specificity Statement: Clone 14 binds human CD8, which is a coreceptor for the T lymphocyte receptor (TCR). CD8 binds, as a heterodimer, to class 1 MHC molecules and facilitates antigen-specific activation of the adaptive immune response. CD8 mutations are associated with various immunodeficiencies and pathologies.

Application Notes (Clone): Clone 14 has been used to investigate the cell type-dependent expression of CD8 in nephrectomised rats by IHC methods (Xiao et al, 2014), and can further be used for detection of T cell population subsets.

• SKU: ABAAb00830-1.1-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00830-1.1-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Immunoprecipitation, Western Blotting, ELISA, Immunohistochemistry, Fluorescence-Activated Cell Sorting (FACS)
• Isotype: IgG1 kappa
• Host: Mouse