Anti-PD-1 (RMP1-14)

Anti-PD-1 (RMP1-14), Recombinant, Bispecific, anti-mPD-L1 kappa, Host: Mouse

CloneID: RMP1-14

Heavy Chain modification: Bispecific antibody

Antigen Long Description: The original rat hybridoma was generated by immunizing Sprague Dawley rats with mouse PD-1-transfectked BHK cells. A P3U1 myeloma was used as the fusion partner.

Buffer Composition: PBS only.

Chimeric Use Statement: This is a bispecific anti-mouse antibody created by fusing anti-PDL-1 VHH domains to the C-terminus of the heavy chains of the anti-mouse PD-1 antibody clone RMP1-14 in a mouse IgG1 D265A format. The mouse IgG1 D265A format is an Fc-silenced format, preve

Specificity Statement: This antibody binds to murine PD-1.

Application Notes (Clone): Binding of the original rat IgG2a antibody to PD1 has been reported to prevent binding of both B7-H1-Ig (PD-L1-Ig) and B7-DC-Ig (PD-L2-Ig) fusion proteins to PD1.

• SKU: ABAAb00813-1.69-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00813-1.69-BT
• Package Unit: 500 μg
• Quantity Unit: STK
• Reactivity: Mouse (Murine)
• Clonality: Recombinant
• Application: Immunohistochemistry (frozen), Flow Cytometry
• Isotype: Bispecific anti-mPD-L1 kappa
• Host: Mouse