CloneID: RMP1-14
Antigen Long Description: The original rat hybridoma was generated by immunizing Sprague Dawley rats with mouse PD-1-transfectked BHK cells. A P3U1 myeloma was used as the fusion partner.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Specificity Statement: This antibody binds to murine PD-1.
Application Notes (Clone): Binding of the original rat IgG2a antibody to PD1 has been reported to prevent binding of both B7-H1-Ig (PD-L1-Ig) and B7-DC-Ig (PD-L2-Ig) fusion proteins to PD1.