Clone Name: HL5104
Light Chain: Kappa
Application Note: WB: 1:500-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 43
Specificity/Sensitivity: This antibody was raised against human Chemokine Receptor D6 Intracellular domain.
Form: Liquid
Buffer (with preservative): PBS, no preservatives.
Concentration: batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. [provided by RefSeq, Jul 2008]
Uniprot ID: O00590
Antigen Species: Human
Immunogen: Recombinant fragment encompassing a sequence within the Intracellular domain of human Chemokine Receptor D6. The exact sequence is proprietary.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: atypical chemokine receptor 2
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