Exarafenib, CAS 2639957-39-2

Product Description: Exarafenib (RAF/KIN_2787) is an orally-available, selective pan-RAF inhibitor. Exarafenib is effective in RAF-dependent cancers, including all classes of BRAF alterations. Exarafenib suppresses MAPK signaling in RAF-dependent melanoma cell lines. Exarafenib has anticancer activity[1][2].

Applications: Cancer-Kinase/protease

Formula: C26H34F3N5O3

References: [1]Miller N, et, al. Antitumor activity of KIN-2787, a next-generation pan-RAF inhibitor, in combination with MEK inhibition in preclinical models of human NRAS mutant melanoma.2022 Jun 2;40(16): e15099./[2]WHO Drug Information. International Nonproprietary Names for Pharmaceutical

CAS Number: 2639957-39-2

Molecular Weight: 521.58

Compound Purity: 99.68

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: p38 MAPK;Raf

• SKU: MEXHY-147268-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-147268-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK