Shelf life (days): 730.0
Formulation: A solution in methyl acetate
Formal Name: 1,1,1,3,3,3-hexafluoropropan-2-yl 4-(3-phenoxybenzyl)piperazine-1-carboxylate
Purity: ≥98%
Formula Markup: C21H20F6N2O3
Formula Weight: 462.4
CAS Number: 1416133-89-5
Notes: JW 642 is an inhibitor of monoacylglycerol lipase (MAGL; IC50s = 3.7, 7.6, and 14 nM for the human, mouse, and rat enzymes, respectively).{20923} It is selective for MAGL over fatty acid amide hydrolase (FAAH; IC50s = 20.6, 31, and 14 µM for the human, mouse, and rat enzymes, respectively), as well as α/β-hydrolase domain-containing protein 6 (ABHD6; IC50s = 107 and 50 nM for the mouse and rat enzymes, respectively).