Deuruxolitinib, CAS 1513883-39-0

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Product Description: Deuruxolitinib, a deuterated Ruxolitinib (HY-50856), is an orally active JAK1 and JAK2 inhibitor. Deuruxolitinib demonstrates significant hair regrowth effects. Deuruxolitinib can be used for the research of alopecia areata[1].

Applications: COVID-19-immunoregulation

Formula: C17H10D8N6

References: [1]Brett King, et al. Efficacy and safety of deuruxolitinib, an oral selective Janus kinase inhibitor, in adults with alopecia areata: Results from the Phase 3 randomized, controlled trial (THRIVE-AA1). J Am Acad Dermatol. 2024 Nov;91(5):880-888./[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

CAS Number: 1513883-39-0

Molecular Weight: 314.41

Compound Purity: 99.18

Research Area: Inflammation/Immunology

Solubility: DMSO : 116.67 mg/mL (ultrasonic)

Target: JAK

• SKU: MEXHY-50856S-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-50856S-50
• Package Unit: 50 mg
• Quantity Unit: STK