Exatecan-d5 (mesylate), CAS 2819276-88-3

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Product Description: Exatecan-d5 (DX8951f-d5) mesylate is deuterium labeled Exatecan mesylate (HY-13631A). Exatecan mesylate is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL). Exatecan mesylate can be used in cancer research[1].

Applications: Cancer-programmed cell death

Formula: C25H21D5FN3O7S

References: [1]Mitsui I, et al. A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo. Jpn J Cancer Res. 1995 Aug;86(8):776-82.

CAS Number: 2819276-88-3

Molecular Weight: 536.58

Compound Purity: 99.83

Research Area: Cancer

Solubility: DMSO : 11.11 mg/mL (ultrasonic)/H2O : 1mg/mL (ultrasonic;warming;heat to 80°C)

Target: ADC Payload;Isotope-Labeled Compounds;Topoisomerase

• SKU: MEXHY-13631AS-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-13631AS-50
• Package Unit: 50 mg
• Quantity Unit: STK