Product Description: Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2][3].
Applications: Cancer-programmed cell death
Formula: C20H32O4
References: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562/[2]S.WCrooks, et al. Leukotriene B4. The International Journal of Biochemistry & Cell Biology Volume 30, Issue 2, 27 March 1998, Pages 173-178./[3]Takehiko Yokomizo, et al. Leukotriene B4: Metabolism and Signal Transduction. Archives of Biochemistry and Biophysics Volume 385, Issue 2, 15 January 2001, Pages 231-241.
CAS Number: 71160-24-2
Molecular Weight: 336.47
Compound Purity: 98.0
Research Area: Cancer; Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: Endogenous Metabolite;Leukotriene Receptor;PROTAC Linkers
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