11β-HSD1-IN-15, CAS 946398-78-3

Product Description: 11β-HSD1-IN-15 is an inhibitor of 11β-hydroxysteroid dehydrogenase type I (11β-HSD1). 11β-HSD1-IN-15 blocks the conversion of corticosterone to cortisol by binding to the active site of the 11β-HSD1 enzyme. 11β-HSD1-IN-15 can be used to investigate the role of 11β-HSD1 enzymes IN the development of metabolic syndrome, obesity, cognitive decline and type 2 diabetes[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C19H18ClF4N3O3S

References: [1]Wan Z K, et al. Efficacious 11β-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model[J]. Journal of medicinal chemistry, 2009, 52(17): 5449-5461.

CAS Number: 946398-78-3

Molecular Weight: 479.88

Research Area: Metabolic Disease

Target: 11β-HSD

• SKU: MEXHY-14156-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-14156-5
• Package Unit: 5 mg
• Quantity Unit: STK