PPARδ agonist 10, CAS 685139-10-0

Product Description: PPARδ agonist 10 (compound 7) is an orally active, selective, and partial agonist of PPARδ, with EC50 values of 0.053 μM and 0.30 µM for hPPARδ(LBD)-GAL4 and mPPARδ, respectively. PPARδ agonist 10 is a partial PPARδ agonist in transactivation assay but a full agonist on free fatty acids (FFA) oxidation in muscle cells both in vitro and in vivo. PPARδ agonist 10 can be used for dyslipidemia research[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: C23H17Br2ClO3S

References: [1]Sauerberg P, et al. Identification and synthesis of a novel selective partial PPARdelta agonist with full efficacy on lipid metabolism in vitro and in vivo. J Med Chem. 2007 Apr 5;50(7):1495-503.

CAS Number: 685139-10-0

Molecular Weight: 568.71

Research Area: Metabolic Disease

Solubility: 10 mM in Ethanol

Target: PPAR

• SKU: MEXHY-121542-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-121542-5
• Package Unit: 5 mg
• Quantity Unit: STK