Uzansertib, CAS 1620012-39-6

Product Description: Uzansertib (INCB053914) is an orally active, ATP-competitive pan-PIM kinase inhibitor with IC50s of 0.24 nM, 30 nM, 0.12 nM for PIM1, PIM2, PIM3, respectively. Uzansertib has broad anti-proliferative activity against a variety of hematologic tumor cell lines[1].

Applications: Cancer-Kinase/protease

Formula: C26H26F3N5O3

References: [1]Koblish H, et al. Preclinical characterization of INCB053914, a novel pan-PIM kinase inhibitor, alone and in combination with anticancer agents, in models of hematologic malignancies. PLoS One. 2018 Jun 21;13(6):e0199108.

CAS Number: 1620012-39-6

Molecular Weight: 513.51

Compound Purity: 99.45

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Pim

• SKU: MEXHY-101870-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-101870-5
• Package Unit: 5 mg
• Quantity Unit: STK