Note: Dry Ice fees will be extra-charged
Products from BPS Bioscience require a minimum order value above 400€
Encompassing Amino Acids: 18-739
Application: Useful for SDS-PAGE.
Assay Conditions: Measured by its ability to cleave a fluorogenic peptide substrate, Mca-YVADAPK(Dnp)-OH.
Background: Angiotensin converting enzyme 2 (ACE2) is an exopeptidase that catalyzes the conversion of angiotensin II to angiotensin 1-7 and L-phenylalanine. Angiotensin II is part of the classical renin angiotensin system (RAS), a hormone system that regulates fluid balance, blood pressure, and maintains vascular tone. ACE2 plays a role in lowering blood pressure and in cardiovascular health and therefore, is an attractive therapeutic target. ACE2 is also the receptor for the human respiratory coronaviruses NL63, SARS (SARS-CoV) and 2019-nCoV/SARS-CoV-2.
Description: Recombinant rhesus macaque angiotensin-converting enzyme 2 (ACE2), encompassing amino acids 18-739. This construct contains a C-terminal His-tag (10xHis) and was affinity purified.
Format: Aqueous buffer solution.
Formulation: Supplied as a 0.22 μm filtered solution of 25 mM Tris-HCl, 150 mM NaCl, 1 mM ZnCl2, and pH 7.5.
Genbank: ACI04564.1
Purity: ≥95% as determined by reducing SDS-PAGE
Storage Stability: Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Tags: His
Target: ACE2
Uniprot: B6DUE2
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
English
Deutsch
