Exosomes

Exosomes

Exosomes have recently became one of the hottest topics in biomedical research. Since 2013 when The Nobel Prize in Physiology or Medicine was awarded to James E. Rothman, Randy W. Schekman and Thomas C. Südhof for their discoveries of machinery regulating vesicle traffic, many research groups have begun to focus on exosomes as a crucial communication and transport tool between the cells in living organisms. Exosomes are supposed to play an active role in cancer spread (Iero M, 2008, Tumour-released exosomes and their implications in cancer immunity) as well as possibly serving as drug delivery vehicles (Kasper Bendix Johnsen, 2014, A comprehensive overview of exosomes as drug delivery vehicles – endogenous nanocarriers for targeted cancer therapy).

For this exciting area of research we offer the following products:

ExoStep™ from Immunostep – Immunobead assay kits for detection and isolation of exosomes for flow cytometry. We offer kits with or without exosome standard, to be used for exosome detection in cell culture supernatant, plasma and urine samples. The kits are available with CD63 capture and CD9 or CD81 exosome marker antibodies.

Single antibodies or antibodies conjugated to magnetic beads, fluorophores or biotin for exosome research – CD9, CD81, CD63, CD326, CD274

Exosome Standards and fluorescent exosome standards isolated from the following cultured cell lines from Abnova – SK-N-SH, HCT116, PC3, BPH-1, U87 MG, COLO1, MM1, BLCL21, DAU1, A549, K562, B16F10.

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  1. ExoELISA-Step for detection and quantification of exosomes from human serum/plasma
    ExoELISA-Step for detection and quantification of exosomes from human serum/plasma
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    Sku IMSExo2508
    Manufact. SkuExo2508
    Packaging Unit96 Tests
  2. ExoELISA-Step for detection and quantification of exosomes from cell culture
    ExoELISA-Step for detection and quantification of exosomes from cell culture
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    Sku IMSExo2506
    Manufact. SkuExo2506
    Packaging Unit96 Tests
  3. Lyophilized Exosome from Caco2 cell line Standards
    Lyophilized Exosome from Caco2 cell line Standards
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    Sku IMSExoCaco2
    Manufact. SkuExoCaco2
    Packaging Unit100 µg
  4. Lyophilized Exosome from Serum Standards
    Lyophilized Exosome from Serum Standards
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    Sku IMSExoSERUM
    Manufact. SkuExoSERUM
    Packaging Unit100 µg
  5. ExoStepTM
    ExoStepTM
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    Sku IMSExoS-50-G81
    Manufact. SkuExoS-50-G81
    Packaging Unit50 Tests
  6. ExoStep Plasma + Standard
    ExoStep Plasma + Standard
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    Sku IMSExoS-50-PST81
    Manufact. SkuExoS-50-PST81
    Packaging Unit50 Tests
  7. ExoStepTM
    ExoStepTM
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    Sku IMSExoS-50-G9
    Manufact. SkuExoS-50-G9
    Packaging Unit50 Tests
  8. ExoStep Culture + Standard
    ExoStep Culture + Standard
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    Sku IMSExoS-50-CST9
    Manufact. SkuExoS-50-CST9
    Packaging Unit50 Tests
  9. Mouse CD63 Capture Beads for Flow Detection
    Mouse CD63 Capture Beads for Flow Detection
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    Sku IMSMO63CB-25
    Manufact. SkuMO63CB-25
    Packaging Unit25 Tests
  10. ExoStep Mouse
    ExoStep Mouse
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    Sku IMSMO2ExoS-25-C9
    Manufact. SkuMO2ExoS-25-C9
    Packaging Unit25 Tests
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