Exosomes

Exosomes

Exosomes have recently became one of the hottest topics in biomedical research. Since 2013 when The Nobel Prize in Physiology or Medicine was awarded to James E. Rothman, Randy W. Schekman and Thomas C. Südhof for their discoveries of machinery regulating vesicle traffic, many research groups have begun to focus on exosomes as a crucial communication and transport tool between the cells in living organisms. Exosomes are supposed to play an active role in cancer spread (Iero M, 2008, Tumour-released exosomes and their implications in cancer immunity) as well as possibly serving as drug delivery vehicles (Kasper Bendix Johnsen, 2014, A comprehensive overview of exosomes as drug delivery vehicles – endogenous nanocarriers for targeted cancer therapy).

For this exciting area of research we offer the following products:

ExoStep™ from Immunostep – Immunobead assay kits for detection and isolation of exosomes for flow cytometry. We offer kits with or without exosome standard, to be used for exosome detection in cell culture supernatant, plasma and urine samples. The kits are available with CD63 capture and CD9 or CD81 exosome marker antibodies.

Single antibodies or antibodies conjugated to magnetic beads, fluorophores or biotin for exosome research – CD9, CD81, CD63, CD326, CD274

Exosome Standards and fluorescent exosome standards isolated from the following cultured cell lines from Abnova – SK-N-SH, HCT116, PC3, BPH-1, U87 MG, COLO1, MM1, BLCL21, DAU1, A549, K562, B16F10.

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  1. NTA analysis of a single sample, BLS1
    NTA analysis of a single sample, BLS1
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    Sku CGSZV-12
    Manufact. SkuZV-12
    Packaging Unit
  2. Analysis service set up
    Analysis service set up
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    Sku CGSZV-1
    Manufact. SkuZV-1
    Packaging Unit
  3. LipoQ Lipid Quantification Assay, 100 tests
    LipoQ Lipid Quantification Assay, 100 tests
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    Sku CGSLP01-100
    Manufact. SkuLP01-100
    Packaging Unit100 tests
  4. Wash Buffer (Concentrate 25x)
    Wash Buffer (Concentrate 25x)
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    Sku CGSEx-P31
    Manufact. SkuEx-P31
    Packaging Unit20 ml
  5. ExoLISA CD81 Exosome Assay
    ExoLISA CD81 Exosome Assay
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    Sku CGSEX503
    Manufact. SkuEX503
    Packaging Unit96 assays
  6. ExoLISA CD63 Exosome Assay
    ExoLISA CD63 Exosome Assay
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    Sku CGSEX502
    Manufact. SkuEX502
    Packaging Unit96 assays
  7. ExoLISA CD9 Exosome Assay
    ExoLISA CD9 Exosome Assay
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    Sku CGSEX501
    Manufact. SkuEX501
    Packaging Unit96 assays
  8. Instant exosomes from A375
    Instant exosomes from A375
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    Sku CGSEX303-50A375
    Manufact. SkuEX303-50A375
    Packaging Unit50 µg
  9. Instant exosomes from LnCAP
    Instant exosomes from LnCAP
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    Sku CGSEX303-50LnCAP
    Manufact. SkuEX303-50LnCAP
    Packaging Unit50 µg
  10. Instant exosomes from A375
    Instant exosomes from A375
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    Sku CGSEX303-250
    Manufact. SkuEX303-250
    Packaging Unit250 µg
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