siRNA/shRNA

siRNA, shRNA

Szabo-Scandic offers a wide range of products for the investigation and elucidation of RNA interference. siRNAs and shRNA (plasmids and lentiviral particles) are available to all putative protein-coding human and murine genes.

  • siRNA gene silencers are provided as a pool of 3 target-specific 19-25 nucleotides (nt) long siRNAs. Each vial is designed to target specifically the gene of interest. The provided amount is sufficient for 50 – 100 transfections.
  • shRNA gene silencer plasmids are offered as a mixture of 3-5 lentiviral plasmids. Each plasmid encodes 19-25 nt (plus 6bp “hairpin loop) shRNA sequence. The product contains 20 µg transfection-ready plasmid DNA which is sufficient for up to 20 transfections. shRNA plasmids enable transient or stable (after puromycin selection) knockdown.
  • shRNA lentiviral particles are supplied as a pool consisting of 3-5 expression constructs. Each individual lentiviral plasmid encodes 19-25 nt short shRNA (plus 6 bp “hairpin-loop”). Cells expressing the desired shRNA, can be selected via the addition of puromycin. Each vial contains 200 µl with 106 infectious lentiviral particles, providing up to 10-20 transductions. Addition of copGFP lentiviral particles to target cells might serve as a control of transduction efficacy. Our lentiviral particles are incapable of replicating and are designed to inactivate themselves after transduction and integration into the genomic DNA of the host cell.

Source: https://www.scbt.com/scbt/product/beta-1-3-gal-t1-sirna-h-shrna-and-lentiviral-particle-gene-silencers?requestFrom=search

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  1. HPV18 E6 siRNA (hpv)
    HPV18 E6 siRNA (hpv)
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    Sku SACSC-270681
    Manufact. Skusc-270681
    Packaging Unit10 µM
  2. p63α shRNA (h) Lentiviral Particles
    p63α shRNA (h) Lentiviral Particles
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    Sku SACSC-37469-V
    Manufact. Skusc-37469-V
    Packaging Unit200 µl
  3. p63α siRNA (h)
    p63α siRNA (h)
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    Sku SACSC-37469
    Manufact. Skusc-37469
    Packaging Unit10 µM
  4. ΔN p63β shRNA (m) Lentiviral Particles
    ΔN p63β shRNA (m) Lentiviral Particles
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    Sku SACSC-37463-V
    Manufact. Skusc-37463-V
    Packaging Unit200 µl
  5. ΔN p63β siRNA (m)
    ΔN p63β siRNA (m)
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    Sku SACSC-37463
    Manufact. Skusc-37463
    Packaging Unit10 µM
  6. p16 INK4A shRNA (m) Lentiviral Particles
    p16 INK4A shRNA (m) Lentiviral Particles
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    Sku SACSC-36144-V
    Manufact. Skusc-36144-V
    Packaging Unit200 µl
  7. p16 INK4A siRNA (m)
    p16 INK4A siRNA (m)
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    Sku SACSC-36144
    Manufact. Skusc-36144
    Packaging Unit10 µM
  8. p16 INK4A shRNA (h) Lentiviral Particles
    p16 INK4A shRNA (h) Lentiviral Particles
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    Sku SACSC-36143-V
    Manufact. Skusc-36143-V
    Packaging Unit200 µl
  9. p16 INK4A siRNA (h)
    p16 INK4A siRNA (h)
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    Sku SACSC-36143
    Manufact. Skusc-36143
    Packaging Unit10 µM
  10. Gα 11 shRNA (r) Lentiviral Particles
    Gα 11 shRNA (r) Lentiviral Particles
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    Sku SACSC-45999-V
    Manufact. Skusc-45999-V
    Packaging Unit200 µl
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