Incucyte® Caspase-3/7 for Metabolism Dye Antibody Labeling Dye

Incucyte® Caspase-3/7 for Metabolism Dye Antibody Labeling Dye
SKU
ESS4776
Packaging Unit
20 µl
Manufacturer
Essen Bioscience

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The Incucyte® Caspase-3/7 for Metabolism Dye couples the activated caspase-3/7 recognition motif (DEVD) with a DNA intercalating dye to enable quantification of apoptosis over time. The Caspase-3/7 for Metabolism Dye is specially formulated for use in the Incucyte® Live-Cell Analysis System, configured with the SX5 Metabolism Optical Module, and can be added directly to tissue culture wells using a no wash, mix and read protocol to acquire live cell images of cells undergoing caspase-3/7 mediated apoptosis. In addition, the Caspase-3/7 for Metabolism Dye is non-perturbing to cell growth and morphology. When added to tissue culture medium, this inert, non- fluorescent substrate crosses the cell membrane where it is cleaved by activated caspase-3/7 resulting in the release of the DNA dye and orange fluorescent staining of nuclear DNA. Kinetic activation of caspase-3/7 can be monitored morphologically using live cell imaging, and quantified using the Incucyte® Basic Analyzer.
More Information
SKU ESS4776
Manufacturer Essen Bioscience
Manufacturer SKU 4776
Package Unit 20 µl
Quantity Unit FL
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