Salicylic acid, CAS 69-72-7

Product Description: Salicylic acid (2-Hydroxybenzoic acid) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation[1].

Applications: COVID-19-immunoregulation

Formula: C7H6O3

Citations: Biopharm Drug Dispos. 2022 Oct 4./bioRxiv. 2023 Jun 3./Food Chem. 2022: 134807./Katedra farmakologie a toxikologie. 2020 Jul./Plant Cell. 2022 Aug 16;koac255./PLoS Biol. 2024 June 27./Cancer Lett. 2021 Jan 1;496:127-133./Commun Biol. 2024 Oct 18;7(1):1346./J Orthop Surg Res. 2023 Dec 15;18(1):967.

References: [1]Mitchell JA, et al. Sodium salicylate inhibits cyclo-oxygenase-2 activity independently of transcription factor (nuclear factor kappaB) activation: role of arachidonic acid. Mol Pharmacol. 1997 Jun;51(6):907-12./[2]Nixon M, et al. Salicylate downregulates 11β-HSD1 expression in adipose tissue in obese mice and in humans, mediating insulin sensitization. Diabetes. 2012 Apr;61(4):790-6.

CAS Number: 69-72-7

Molecular Weight: 138.122

Compound Purity: 98.42

Research Area: Inflammation/Immunology; Cancer

Solubility: DMSO : ≥ 50 mg/mL/H2O : 1 mg/mL (ultrasonic)

Target: Apoptosis;Autophagy;COX;Endogenous Metabolite;Mitophagy

• SKU: MEXHY-B0167-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B0167-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK