Inhibitory monoclonal antibody to human prorenin, clone 4B5-E3

Inhibitory monoclonal antibody to human prorenin, clone 4B5-E3, Isotype: IgG2, 0,1 mg
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Molecular Weight: 160000
Storage Buffer: 0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6
Source: Hybridoma cell culture
Extinction coefficient: 1,36
Antigen: Recombinant full length wild-type human protein (Glycosylated).
Target: Recognises amino acid residues 30-43 (MARLGPEWSQPMKR) of the prosegment of prorenin.
Target molecular weight: 43725
Purity: IgG fraction
Gene: REN
Swiss ID: P00797
Description: Inhibitory mouse monoclonal antibody directed to human prorenin (Patent Pending). This antibody recognizes and binds only to prorenin. It does not bind or otherwise interact with active renin. Blocks proteolytic conversion of prorenin to renin by catalytic amounts of trypsin (unpublished data). Binding epitope is within amino acid residues 30-43 (MARLGPEWSQPMKR) of prorenin. Strongly blots prorenin under non-reducing and reducing conditions. No cross reactivity with mouse or rat prorenin. IgG fraction purified by immobilized Protein A. Clone 4B5-E3, isotype IgG2b.
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Artikelnummer MOIPREN4B5E3-0,1
Hersteller Molecular Innovations
Hersteller Artikelnummer PREN4B5E3-0,1
Verpackungseinheit 0,1 mg
Mengeneinheit FL
Reaktvität Human
Klonalität Monoclonal
Methode Western Blotting, ELISA, Blocking, Inhibitory Antibody
Isotyp IgG2b
Human Gene ID 5972
Wirt Mouse
MSDS Download