Human Prolactin Receptor, chiMAX Fc Fusion Protein

Human Prolactin Receptor, chiMAX Fc Fusion Protein, 0,1 mg
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Molecular Weight: 51000
Storage Buffer: PBS
Source: Insect cell culture
Activity: ED50 < 1 ug/ml in the presence of 0.5 ng/ml of recombinant human prolactin as determined in a cell proliferation assay using Nb2-11 rat lymphoma cells.
Purity: >95% by SDS-PAGE analysis
Gene: PRLR
Swiss ID: P16471
Description: Prolactin is a neuroendocrine peptide hormone that is secreted primarily by the pituitary gland. Prolactin receptor is a class 1 cytokine transmembrane receptor that varies in size with tissue source and species. It consists of an extracellular region with 5 cysteines which contains the prolactin binding site, a single transmembrane domain and a cytoplasmic region. The extracellular domain (Gln25-Asp234) is expressed recombinantly, purified by chromatography, sterile filtered and lyophilized. >95percent pure by SDS-PAGE and biologically active as measured by inhibitory activity toward prolactin-induced proliferation of Nb2-11 rat lymphoma cells (Gout et al. (1980) Cancer Res. 40:2433). ED50 for this effect is typically < 1.0 ug/ml in the presence of 0.5 ng/ml of recombinant human Prolactin. Add deionized water to original volume, aliquot and freeze unused portion.
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Artikelnummer MOIHPRLR-FC-0,1
Hersteller Molecular Innovations
Hersteller Artikelnummer HPRLR-FC-0,1
Verpackungseinheit 0,1 mg
Mengeneinheit FL
Reaktvität Human
Human Gene ID 5618
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