Molecular Weight: 170000
Storage Buffer: 0.02M Sodium Phosphate; 0.15M NaCl; 0.05% Azide; pH 7.4
Source: Human plasma
Extinction coefficient: 1,36
Purity: >95% by SDS-PAGE analysis
Swiss ID: P01860
Description: Like IgG1, IgG3 activates complement and has an affinity for fc receptors; thus IgG1 and IgG3 are the more effective of the IgG subclasses. An IgG3 deficiency is associated with Wiscott-Aldrich disease, systemic lupus erythematosus, juvenile diabetes mellitus, and peridontal infections. IgG anti-viral antibodies are restricted to IgG subclasses 1 and 3, with IgG3 antibodies being the first to appear in response to infection. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.