Mouse Erythropoietin, chiMAX Fc Fusion Protein

Mouse Erythropoietin, chiMAX Fc Fusion Protein, 0,1 mg
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Molecular Weight: 48700
Storage Buffer: PBS
Source: Insect cell culture
Extinction coefficient: 1,05
Activity: ED50 < 5 ng/ml as determined in a cell proliferation assay using human TF-1 erythroleukemia cells.
Purity: >95% by SDS-PAGE analysis
Gene: EPO
Swiss ID: Q0VED9
Description: Erythropoietin (EPO) is a glycoprotein hormone related to Thrombopoietin which stimulates erythrocyte formation by inhibiting apoptosis of early erythroidprecursors. Mouse EPO (Ala27-Arg192) is expressed recombinantly, purified by chromatography, sterile filtered and lyophilized. >95percent pure by SDS-PAGE and biologically active as measured in a proliferation assay with human TF-1 erythroleukemia cells (Kitamura et al. (1989) J. Cell Physiol. 140:323). The ED50 for this activity is typically < 5 ng/ml. Add deionized water to original volume, aliquot and freeze unused portion.

This chiMAX Fc Fusion Protein is glycosylated and expressed as a chimera with the Fc region of mouse immunoglobulin (heavy chain hinge, CH2 and CH3). Fc fusion proteins are typically more stable and resistant to degradation and clearance than native cytokines. Fc fusion proteins appear as a dimer in SDS-PAGE under non-reducing conditions.
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Artikelnummer MOIMEPO-FC-0,1
Hersteller Molecular Innovations
Hersteller Artikelnummer MEPO-FC-0,1
Verpackungseinheit 0,1 mg
Mengeneinheit FL
Reaktvität Mouse (Murine)
Human Gene ID 13856
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