Molecular Weight: 43000
Storage Buffer: PBS, 0.1% BSA
Source: Insect cell culture
Extinction coefficient: 0,9
Activity: ED50 < 5 ng/ml as determined in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells.
Purity: 98% by SDS-PAGE analysis
Swiss ID: P04351
Description: Interleukin-2 (IL-2) is a O-glycosylatedfour alpha-helix bundle cytokine that is produced by T-cells in response to antigenic or mitogenic stimulation. IL-2 can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells and is required for T-cell proliferation and other activities crucial to regulation of the immune response. Mouse IL-2 (Ala21-Gln169) is expressed recombinantly, purified by chromatography, sterile filtered and lyophilized. >95percent pure by SDS-PAGE and biologically active as measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T-cells. (Gearing and Bird (1987) Production and assay of interleukin 2. In Lymphokines and Interferons: A Practical Approach (Clemens et al. eds.) pp. 291-301). The ED50 for this effect is typically < 1.0 ng/ml. Add deionized water to original volume, aliquot and freeze unused portion.