Recombinant Herpes simplex virus type 2 ICP47 protein(US12)

Recombinant Herpes simplex virus type 2 ICP47 protein(US12)
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Organism: Herpes simplex virus type 2 (strain SA8) (Simian agent 8). Function: Plays a role in the inhibition of host immune response. Binds specifically to transporters associated with antigen processing (TAP), thereby blocking peptide-binding and translocation by TAP as well as subsequent loading of peptides onto MHC class I molecules. Empty MHC I molecules are retained in the endoplasmic reticulum and ultimately directed to proteasomal degradation. In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes. Subcellular Location: Host cytoplasm, Host nucleus. Protein Families: Herpesviridae US12 family. Tag Info: N-terminal 6xHis-KSI-tagged
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Artikelnummer CSB-EP353051HGH-1
Hersteller Cusabio
Hersteller Artikelnummer CSB-EP353051HGH-1
Verpackungseinheit 1 mg
Mengeneinheit FL
Wirt Escherichia Coli