Recombinant Human Negative regulator of reactive oxygen species(NRROS),partial

Recombinant Human Negative regulator of reactive oxygen species(NRROS),partial
Artikelnummer
CSB-BP801264HU-1
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Organism: Homo sapiens (Human). Function: Negative regulator of reactive oxygen species (ROS) that limits ROS production by phagocytes during inflammatory response, thereby playing a role during host defense. Acts via direct interaction with CYBB/NOX2 monomer that impairs interaction between CYBB/NOX2 and CYBA/p22-phox and formation of a stable NOX2 complex (By similarity). May play a critical role in desensitizing TLR signaling through inhibition of Toll-like receptor-mediated NF-kappa-B activation and cytokine production. Subcellular Location: Cell membrane, Single-pass type I membrane protein, Endoplasmic reticulum membrane, Single-pass type I membrane protein. Tissue Specificity: Ubiquitous, with high level of expression found in bone marrow, thymus, liver, lung, intestine and spleen. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged
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Artikelnummer CSB-BP801264HU-1
Hersteller Cusabio
Hersteller Artikelnummer CSB-BP801264HU-1
Verpackungseinheit 1 mg
Mengeneinheit FL
Reaktvität Human
Methode Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis (SDS-PAGE)
Wirt Various hosts
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