Recombinant Human TGF-beta-activated kinase 1 and MAP3K7-binding protein 2(TAB2),partial

Recombinant Human TGF-beta-activated kinase 1 and MAP3K7-binding protein 2(TAB2),partial
Artikelnummer
CSB-BP868358HU-1
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Organism: Homo sapiens (Human). Function: Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development. Involvement in disease: Congenital heart defects, multiple types, 2 (CHTD2). Subcellular Location: Membrane, Peripheral membrane protein, Cytoplasm, cytosol. Tissue Specificity: Widely expressed. In the embryo, expressed in the ventricular trabeculae, endothelial cells of the conotruncal cushions of the outflow tract and in the endothelial cells lining the developing aortic valves. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged
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Artikelnummer CSB-BP868358HU-1
Hersteller Cusabio
Hersteller Artikelnummer CSB-BP868358HU-1
Verpackungseinheit 1 mg
Mengeneinheit FL
Reaktvität Human
Wirt Various hosts
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