Recombinant Lake Victoria marburgvirus Envelope glycoprotein(GP),partial

Recombinant Lake Victoria marburgvirus Envelope glycoprotein(GP),partial
Artikelnummer
CSB-BP330440LBR-1
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Organism: Lake Victoria marburgvirus (strain Popp-67) (MARV) (Marburg virus (strain West Germany/Popp/1967)). Function: GP1 is responsible for binding to the receptor(s) on target cells. Interacts with CD209/DC-SIGN and CLEC4M/DC-SIGNR which act as cofactors for virus entry into the host cell. Binding to CD209 and CLEC4M, which are respectively found on dendritic cells (DCs), and on endothelial cells of liver sinusoids and lymph node sinuses, facilitate infection of macrophages and endothelial cells. These interactions not only facilitate virus cell entry, but also allow capture of viral particles by DCs and subsequent transmission to susceptible cells without DCs infection (trans infection) (By similarity). Subcellular Location: GP2: Virion membrane, Single-pass type I membrane protein, Host cell membrane, Single-pass type I membrane protein, Note=In the cell, localizes to the plasma membrane lipid rafts, which probably represent the assembly and budding site, SUBCELLULAR LOCATION: GP1: Virion membrane, Peripheral membrane protein, Host cell membrane, Peripheral membrane protein. Protein Families: Filoviruses glycoprotein family. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged
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Artikelnummer CSB-BP330440LBR-1
Hersteller Cusabio
Hersteller Artikelnummer CSB-BP330440LBR-1
Verpackungseinheit 1 mg
Mengeneinheit FL
Wirt Various hosts
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