Recombinant Macaca fascicularis Legumain(LGMN)

Recombinant Macaca fascicularis Legumain(LGMN)
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Organism: Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey). Function: Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system (By similarity). Subcellular Location: Lysosome. Protein Families: Peptidase C13 family. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged
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Artikelnummer CSB-BP012903MOVB1-1
Hersteller Cusabio
Hersteller Artikelnummer CSB-BP012903MOVB1-1
Verpackungseinheit 1 mg
Mengeneinheit FL
Reaktvität Cynomolgus Monkey (Primate)
Methode Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis (SDS-PAGE)
Wirt Various hosts