Molecular Weight: 75,000 (Approximate)
Storage Buffer: 4 mM Sodium Acetate; 0.15 M NaCl; pH 5.3
Source: Insect cell culture
Extinction coefficient: 1,73
Purity: >95% by SDS-PAGE analysis
Swiss ID: Q80YC5
Description: Recombinant insect cell derived mouse Factor XII is a single chain glycoprotein purified by ion exchange chromatography. Factor XII is converted, principally from the action of kallikrein, into an active serine protease (Factor alpha-XIIa) that functions in the in vivo initiation of blood coagulation, fibrinolysis, and kinin formation. The protein purity is determined by SDS-PAGE and activity is determined via complementation in an APTT clotting assay using Factor XII immuno-deficient human plasma.