Recombinant Mouse Glypican-1(Gpc1)

Recombinant Mouse Glypican-1(Gpc1)
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Species: Mus musculus (Mouse). Function: Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling. Binds Cu(2+) or Zn(2+) ions. Subcellular Location: Cell membrane, Lipid-anchor, GPI-anchor, Extracellular side, Endosome. Protein Families: Glypican family. Tag Info: C-terminal 6xHis-tagged.
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Artikelnummer CSB-AP005761MO-1
Hersteller Cusabio
Hersteller Artikelnummer CSB-AP005761MO-1
Verpackungseinheit 1 mg
Mengeneinheit FL
Wirt Mammalian Cell