Recombinant Mouse Peroxisome proliferator-activated receptor gamma(Pparg)

Recombinant Mouse Peroxisome proliferator-activated receptor gamma(Pparg)
Artikelnummer
CSB-EP018424MO-1
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Organism: Mus musculus (Mouse). Function: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL/BMAL1 in the blood vessels. Subcellular Location: Nucleus, Cytoplasm. Protein Families: Nuclear hormone receptor family, NR1 subfamily. Tissue Specificity: Highest expression in white and brown adipose tissue. Also found in liver, skeletal muscle, heart, adrenal gland, spleen, kidney and intestine. Isoform 2 is more abundant than isoform 1 in adipose tissue. Tag Info: N-terminal 6xHis-SUMO-tagged
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Artikelnummer CSB-EP018424MO-1
Hersteller Cusabio
Hersteller Artikelnummer CSB-EP018424MO-1
Verpackungseinheit 1 mg
Mengeneinheit FL
Wirt Escherichia Coli
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