Recombinant Mouse Serine/threonine-protein kinase STK11(Stk11)

Recombinant Mouse Serine/threonine-protein kinase STK11(Stk11)
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Organism: Mus musculus (Mouse). Function: Tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts by phosphorylating the T-loop of AMPK family proteins, thus promoting their activity. Subcellular Location: Nucleus, Cytoplasm, Membrane, Mitochondrion, Note=Translocates to mitochondrion during apoptosis (By similarity), A small fraction localizes at membranes, Relocates to the cytoplasm when bound to STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), PTEN promotes cytoplasmic localization (By similarity), SUBCELLULAR LOCATION: Isoform 2: Nucleus, Cytoplasm. Protein Families: Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamily. Tissue Specificity: Widely expressed. Isoform 2 is predominantly expressed in testis (at protein level). Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged
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Artikelnummer CSB-BP893402MO-1
Hersteller Cusabio
Hersteller Artikelnummer CSB-BP893402MO-1
Verpackungseinheit 1 mg
Mengeneinheit FL
Methode Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis (SDS-PAGE)
Wirt Various hosts