Recombinant Mouse Transmembrane protease serine 6(Tmprss6),partial

Recombinant Mouse Transmembrane protease serine 6(Tmprss6),partial
Artikelnummer
CSB-BP880561MO-1
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Organism: Mus musculus (Mouse). Function: Serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. Can also activate urokinase-type plasminogen activator with low efficiency. May play a specialized role in matrix remodeling processes in liver. Through the cleavage of HFE2, a regulator of the expression of the iron absorption-regulating hormone hepicidin/HAMP, plays a role in iron homeostasis. Subcellular Location: Cell membrane, Single-pass type II membrane protein. Protein Families: Peptidase S1 family. Tissue Specificity: Expressed at highest levels in adult mice liver, kidney and uterus. Also strongly expressed within the nasal cavity by olfactory epithelial cells. A weak, but detectable, signal in adult mice tissues analyzed including brain, lung, heart, kidney, spleen, muscle, intestine, thymus and pancreas. No signal in residual embryonic yolk sac, developing kidney tubules or in embryonic tissues analyzed including lung, heart, gastrointestinal tract and epithelium of the oral cavity. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged
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Artikelnummer CSB-BP880561MO-1
Hersteller Cusabio
Hersteller Artikelnummer CSB-BP880561MO-1
Verpackungseinheit 1 mg
Mengeneinheit FL
Methode Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis (SDS-PAGE)
Wirt Various hosts
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