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Anti-Human CD7 In Vivo Antibody - Low Endotoxin (T3-3A1)

Anti-Human CD7 In Vivo Antibody - Low Endotoxin (T3-3A1)
899,30 €
Artikelnummer: ICH1158-25MG

Verfügbarkeit: Lieferzeit auf Anfrage

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Anti-Human CD7 In Vivo Antibody - Low Endotoxin (T3-3A1), Host: Mouse, IgG1

Details

Clone: T3-3A1.
Target: CD7.
Specificity: Clone T3-3A1 recognizes an epitope on human CD7.
Purification Method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution: CD7 is expressed on T cells, NK cells, thymocytes, hematopoietic progenitors, some normal B cells, malignant B cells, acute lymphocytic leukemia (ALL) cells, and some acute myeloid leukemia (AML) cells. It is weakly expressed on monocytes.

Background: CD7 is a 40 kD type I transmembrane glycoprotein and is a member of the Ig superfamily. It plays a vital role in T-cell interactions, in adition to, T-cell/B-cell interaction during early lymphoid development, and has been shown to interact with PIK3R1. Functional studies indicate that crosslinking of the CD7 can stimulate transmembrane calcium flux in T cells. Lack of CD7 expression can help to diagnose T-cell lymphoproliferative disorders, such as mycosis fungoides/Sezary syndrome and adult T-cell leukemia/lymphoma.

Purity: >95% by SDS-PAGE and HPLC.
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method.

Zusatzinformation

Artikelnummer ICH1158-25MG
Hersteller Ichorbio
Herstellernummer ICH1158-25MG
Verpackungseinheit 25 mg
Mengeneinheit FL
Reaktivität Mouse (Murine)
Klonalität Monoclonal
Wirt / Host Mouse
Methode Flow Cytometry, Immunofluorescence
Isotype IgG1
Gene ID Keine Herstellerangabe
Datenblatt Download
MSDS Auf Anfrage