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Anti-Mouse CD25 In Vivo Antibody - Low Endotoxin (7G7B6)

Anti-Mouse CD25 In Vivo Antibody - Low Endotoxin (7G7B6)
150,35 €
Artikelnummer: ICH1163-1MG

Verfügbarkeit: Lieferzeit auf Anfrage

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Anti-Mouse CD25 In Vivo Antibody - Low Endotoxin (7G7B6), Host: Mouse, IgG2a


Clone: 7G7B6.
Target: CD25.
Specificity: Clone 7G7B6 reacts with human CD25.
Immunogen: This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Purification Method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution: IL-2Rα is expressed on activated mature T and B lymphocytes, during early stages of thymocytes development, pre-B cells, and in activated CD4+ memory T-lymphocytes.

Background: CD25 (IL-2Rα) is the 55 kDa subunit of the interleukin 2 receptor alpha chain which has been shown to play roles in lymphocyte differentiation, activation, and proliferation. IL-2Rα is a transmembrane glycoprotein comprised of a heavily glycosylated extracellular domain, a transmembrane region and a short cytoplasmic tail. IL-2Rα heterodimerizes with IL-2Rβ (CD122) and IL-2Rγ (CD132) and forms the IL-2 receptor complex. IL-2Rα by itself binds IL-2 with relatively low affinity, while the IL-2 receptor complex binds IL-2 with high affinity. IL-2Rα mutations cause severe immunodeficiency.

Purity: >95% by SDS-PAGE and HPLC.
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method.


Artikelnummer ICH1163-1MG
Hersteller Ichorbio
Herstellernummer ICH1163-1MG
Verpackungseinheit 1 mg
Mengeneinheit FL
Reaktivität Human
Klonalität Monoclonal
Wirt / Host Mouse
Methode ELISA, Flow Cytometry, Immunofluorescence, Immunoprecipitation, Western Blotting
Isotype IgG2a
Gene ID Keine Herstellerangabe
Datenblatt Download
MSDS Auf Anfrage