beta Catenin antibody (CTNNB1/2098)

beta Catenin antibody (CTNNB1/2098)
Artikelnummer
GTX17954-100
Verpackungseinheit
100 μg
Hersteller
GeneTex

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Clone Name: CTNNB1/2098

Light Chain: Kappa

Application Note: IHC-P: 1-2μg/ml for 30 minutes at RT. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 86

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA, 0.05% Sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]

Uniprot ID: P35222

Antigen Species: Human

Immunogen: Recombinant full-length human beta-Catenin (CTNNB1) protein

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: catenin beta 1
Mehr Informationen
Artikelnummer GTX17954-100
Hersteller GeneTex
Hersteller Artikelnummer GTX17954-100
Verpackungseinheit 100 μg
Mengeneinheit STK
Reaktivität Human
Klonalität Monoclonal
Methode Immunohistochemistry (paraffin), Protein Array
Isotyp IgG2b
Human Gene ID 1499
Wirt Mouse
Produktinformation (PDF) Download
MSDS (PDF) Download