CD11c antibody (ITGAX/2507)

Clone Name: ITGAX/2507

Light Chain: Kappa

Application Note: ELISA: 1-5μg/ml (for coating). *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 128

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA, 0.05% Sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

Uniprot ID: P20702

Antigen Species: Human

Immunogen: Recombinant fragment of human ITGAX protein (around aa 637-827) (exact sequence is proprietary)

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: integrin subunit alpha X