Clone Name: MEM-15
Application Note: FACS: 4 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 40
Specificity/Sensitivity: This antibody reacts with CD14, a 53-55 kDa GPI (glycosylphosphatidylinositol)-linked membrane glycoprotein expressed on monocytes, macrophages and weakly on granulocytes; also expressed by most tissue macrophages. And this antibody also reacts with soluble forms of CD14 found in serum and in the urine of some nephrotic patients.
Form: Liquid
Buffer (with preservative): PBS, 15mM Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Notes: For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.
Background: The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010]
Uniprot ID: P08571
Antigen Species: Human
Immunogen: A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria.
Purification: Purified by size-exclusion chromatography
Conjugation: PE-Cy7
Full Name: CD14 molecule